Which two consequences commonly occur with ileal resection due to bile salt reabsorption?

Which two consequences commonly occur with ileal resection due to bile salt reabsorption?

• A. Increased bile salt pool and fat absorption
• B. Decreased gastric acid secretion
• C. Bile salt pool is depleted with reduced fat absorption; diarrhea from colon water/salt loss
• D. No effect on fat absorption

Answer: (C)

When the ileum is resected, bile acids can no longer be reabsorbed efficiently and are lost in the stool. Bile acids are normally recycled through enterohepatic circulation, and losing them depletes the body's bile salt pool. With fewer bile acids available, fat emulsification and micelle formation are impaired, leading to reduced fat absorption. The unabsorbed bile acids that reach the colon stimulate water and electrolyte secretion, producing diarrhea. So, two common consequences are a depleted bile salt pool with reduced fat absorption and diarrhea from colon water/salt loss. The other options don’t fit because bile acid pool would not increase, gastric acid secretion isn’t a primary consequence of ileal bile acid loss, and fat absorption is indeed affected.

When the ileum is resected, bile acids can no longer be reabsorbed efficiently and are lost in the stool. Bile acids are normally recycled through enterohepatic circulation, and losing them depletes the body's bile salt pool. With fewer bile acids available, fat emulsification and micelle formation are impaired, leading to reduced fat absorption. The unabsorbed bile acids that reach the colon stimulate water and electrolyte secretion, producing diarrhea. So, two common consequences are a depleted bile salt pool with reduced fat absorption and diarrhea from colon water/salt loss. The other options don’t fit because bile acid pool would not increase, gastric acid secretion isn’t a primary consequence of ileal bile acid loss, and fat absorption is indeed affected.